Clinical analysis of stent thrombosis after implantation of domestic cobalt-chromium drug-eluting stents
- VernacularTitle:国产钴铬合金平台药物洗脱支架植入术后支架内血栓形成的临床分析
- Author:
Ji-E YANG
1
;
Wu-Xu ZUO
;
Yue-Yi PAN
;
Feng ZHANG
;
Ju-Ying QIAN
;
Lei GE
;
Jun ZHOU
;
Dong HUANG
;
Jian-Ying MA
;
Kang YAO
;
Jun-Bo GE
Author Information
1. 复旦大学附属中山医院心内科
- Keywords:
drug-eluting stent;
stent thrombosis;
dual antiplatelet therapy
- From:
Chinese Journal of Clinical Medicine
2016;23(3):282-285
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the occurence and prognosis of stent thrombosis (ST ) after implantation of the Firebird 2 cobalt-chromium drug-eluting stent (DES) so as to provide abundant clinical evidence for the wide application of domestic second-generation drug-eluting stents .Methods: This study retrospectively analyzed 5 084 DES patients on the Firebird 2 cobalt-chromium alloy platform during the 3-year follow-up in the large-scale ,international ,multicenter FOCUS registry .Three-year cumulative incidence of ST was reported .The clinical features of ST patients ,duration of dual antiplatelet therapy (DAPT ) , and the treatment and as prognosis of ST were the main focuses of this study .Results: The 3-year cumulative incidence of ST was 0 .67% (35 cases) ,including 8 cases of acute ST ,11 cases of subacute ST ,8 cases of late ST and 8 cases of very late ST .Among them ,28 patients of ST were recovered after re-intervention or thrombolysis ,while 7 patients were died because of treatment failure .The mortality of ST patients was 20 .6% .All ST patients were treated with DAPT for at least 12 months except for 3 patients who had stopped taking DAPT and 1 patient who took clopidegrel only . Conclusions:The 3-year follow-up FOCUS study shows that , the cumulative incidence of ST is less than 1% after DES implantation on the domestic second-generation Firebird 2 cobalt-chromium alloy platform ,providing reliable safety evidence for the clinical application of Firebird 2 stents .
