Efficacy Analysis of Combination Drug Therapy for Chronic Prostatitis:Report of 253 Cases
- VernacularTitle:联合药物治疗慢性前列腺炎的疗效分析：附253例报告
- Author:
Qiang MA
1
;
Zhuo CHEN
;
Guojin JIA
;
Wei JIN
;
Xueqiang LU
;
Xuefeng XIE
Author Information
1. 复旦大学附属金山医院泌尿外科
- Keywords:
Chronic prostatitis;
Quinolone;
Alpha blocker;
Prostat
- From:
Chinese Journal of Clinical Medicine
2015;(5):631-632
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the efficacy of combination drug therapy for chronic prostatitis .Methods:According to National Institute Health Chronic Prostatitis Syndrome Index (NIH‐CPSI) combined with the pre‐ and post‐ massage test (PPMT) and expressed prostatic secretion (EPS) routine examination ,the NIH classification and efficacy evaluation was conducted for 253 patients with chronic prostatitis .All the 253 cases were administered quinolone antibiotics for 2 to 4 weeks , and meanwhile were administered alpha blocker and prostat for 4 to 6 weeks .Results:According to NIH‐CPSI ,there were 23 (9 .1% ) cases of type Ⅱ ,109(43 .1% ) cases of type Ⅲ A and 121(47 .8% ) cases of type Ⅲ B among the 253 patients .After 6 weeks of treatment ,the patients were evaluated by CPSI and the results showed that the curative rate ,the remarkable effective rate ,the improving rate ,the ineffective rate ,the total effective rate was 18 .6% ,45 .5% ,14 .6% ,21 .3% ,and 77 .7% , respectively .The average WBC count in EPS was (5 .4 ± 1 .6)/HP after the treatment ,while it was (24 .6 ± 3 .8)/HP before the treatment .And the difference was statistically significant (P< 0 .05) .After the treatment ,23 patients with chronic bacterial prostatitis underwent bacterial culture by using PPMT ,19 of which turned negative with a turning negative rate of 82 .6% .Conclusions:NIH‐CPSI is a reliable method for efficacy evaluation .The combination of drugs ,including quinolone , alpha blockade and prostat ,shows satisfactory effect for the treatment of chronic prostatitis .
