Anti-Müllerian Hormone as Predictor of Ovarian Response in Women with Polycystic Ovary Syndrome
- VernacularTitle:抗苗勒管激素对多囊卵巢综合征卵巢反应的预测作用
- Author:
Suying LIU
1
;
Jun XU
;
Xiang CAO
;
Lin WANG
;
Xi DONG
Author Information
1. 复旦大学附属中山医院生殖科
- Keywords:
Anti-Müllerian hormone;
Polycystic ovary syndrome;
In vitro fertilization
- From:
Chinese Journal of Clinical Medicine
2015;(5):621-623
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the predictive value of anti‐Müllerian hormone (AMH) in in vitro fertilization (IVF) procedure of women with polycystic ovary syndrome (PCOS) .Methods:A total of 80 patients with PCOS who received IVF treatment were selected during January 2011 to December 2014 in Zhongshan Hospital ,Fudan University .Enzyme‐linked immunoassay (ELISA) was applied to detect the serum levels of AM H ,and microparticle chemiluminescent immunoassay was used to detect the levels of follicle stimulating hormone (FSH) ,luteinizing hormone (LH) and estradiol (E2 ) .Results:Serum AMH([30 .35 ± 9 .22] pmol/L vs .[14 .92 ± 4 .20] pmol/L)and LH([10 .36 ± 3 .16] IU/L vs .[5 .73 ± 2 .36] IU/L) in patients of PCOS groups were significantly higher than those in control group (P< 0 .05) .Compared with the low oocytes group ,the AMH in the normal response group was significantly increased (P< 0 .05) .Compared with the normal response group ,the AM H in the high response group was significantly increased (P<0 .01) .There was a positive relationship between serum AM H and occytes obtained .Conclusions:Serum AM H level has a predictive value in the ovarian response in patients w ith PCOS .
