Analysis of the Relationship between Serum Adiponectin and Arteriosclerosis in Peritoneal Dialysis Patients
- VernacularTitle:腹膜透析患者的血清脂联素与动脉粥样硬化的关系
- Author:
Lizhen WANG
1
;
Xiaorong BAO
Author Information
1. 复旦大学附属金山医院肾内科
- Keywords:
Peritoneal dialysis;
Adiponectin;
C reactive protein;
Inflammation
- From:
Chinese Journal of Clinical Medicine
2015;(4):536-538
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the relationship between arteriosclerosis and inflammatory status and adiponectin (ADPN) in peritoneal dialysis patients.Methods:A total of 48 stable peritoneal dialysis patients were enrolled,and C reactive protein (CRP)and ADPN in the serum were measured.Arteriosclerosis (AS)was detected by vascular ultrasound.Then the relation-ships between them were analyzed.Results:Compared with the no-AS group,the AS group had significant lower level of AD-PN (P <0.01)and significant higher level of CRP (P <0.01).The level of ADPN was lower in the high CRP group than that in the normal CRP (P <0.01).Pearson correlation analysis showed that CRP had a significant negative correlation with ADPN (P <0.01).Conclusions:Low serum ADPN level in peritoneal dialysis patients can aggravate inflammatory staus,and promote arteriosclerosis.
