Vitamin D in the Treatment of Prostate Cancer:A Meta-Analysis
- VernacularTitle:维生素D治疗前列腺癌的Meta分析
- Author:
Jun XIANG
1
;
Cuidong BIAN
;
Shengsong HUANG
;
Denglong WU
Author Information
1. 同济大学附属同济医院泌尿外科
- Keywords:
Vitamin D;
Prostate cancer;
Meta-analysis
- From:
Chinese Journal of Clinical Medicine
2015;(4):528-530
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To evaluate the effects of vitamin D supplement on the mortality and incidence rate of adverse events of prostate cancer.Methods:Date from PubMed,The Cochrane Library,CNKI,Wanfang Data and VIP database during the date of database establishment and April 2014 were searched online,while relevant journals were searched manually,for all rando-mized controlled trials (RCTs)of comparison between vitamin D and placebo in the treatment of prostate cancer.The data ex-traction and quality assessment were conducted according to inclusion and exclusion criteria by two reviewers independently with RevMan5.2.Results:A total of 3 RCTs involving 2243 cases met the inclusion criteria.Vitamin D could reduce the mor-tality of prostate cancer[OR=0.23,95%CI:0.1 8-0.29],as meta-analysis demonstrated.There was no report on adverse e-vents.Conclusions:Vitamin D could reduce the mortality of prostate cancer.However,the analysis is secondary study,of which the included literatures differ in quality,and there may be bias in analytical process.Thus,basic and clinical researches with large-scale and high-quality should be performed to confirm the above conclusion.
