Effect of Management Specification of Cervical Ripening with Dinoprostone Suppository on Pregnancy Out-come
- VernacularTitle:地诺前列酮栓促宫颈成熟管理规范对妊娠结局的影响
- Author:
Xiang JIANG
1
;
Zhenli SHAN
;
Ming LIU
;
Chuanlu XU
;
Xiaohu QIAN
;
Ye WANG
;
Ying YUAN
;
Dan LIU
Author Information
1. 同济大学附属第一妇婴保健院妇产科
- Keywords:
Dinoprostone suppository;
Cervical ripening;
Pregnancy outcome;
Adverse reactions
- From:
Chinese Journal of Clinical Medicine
2015;(3):390-393
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To compare the pregnancy outcome before the implementation of management specification of cervical ripening with dinoprostone suppository with that after the implementation and explore its safety for cervical ripening .Methods:The clinical data of 612 puerperants ,who received cervical ripening with dinoprostone suppository and delivered in First Mater‐nal and Infant Hospital Affiliated to Tongji University during Sep 2012 and Feb 2014 ,were retrospectively analyzed .The man‐agement specification of cervical ripening with dinoprostone had been implemented since Apr 2013 .The maternal and neonatal outcomes ,as well as the rate of adverse reactions ,before and after the implementation of management specification of cervical ripening with dinoprostone suppository were compared with each other ,so as to explore its effects on pregnancy outcome .Re‐sults:There were 449 puerperants receiving cervical ripening with suppository before the implementation of management speci‐fication in Apr 2013 and 163 cases after that .Totally 413 cases(67 .5% ) were induced labour successfully .The success rates of inducting labor within 48 h ,24 h and 12 h after the implementation of management specification were lower than that before the implementation of management specification ,but there was no significant difference .The cesarean rate was 27 .1% and there was no statistically significant difference between the cesarean rate before the implementation of management specification and that after the implementation .There was no statistically significant difference in Apgar score and admission rate to ICU between the two groups .The incidence rates of tachysystole and hypertonus ,meconium‐stained amniotic fluid after the implementation of specification were significantly lower than that before the implementation ,and the difference was statistically significant(P<0 .05) .There was no statistically significant difference regarding the incidence rates of uterine hyperstimulation and the clinical chorioamnionitis .There was no occurrence of complications as amniotic fluid embolism and severe perineal laceration .Conclusions:Di‐noprostone suppository is a safe and effective method for cervical ripening and labor induction .The implementation of management speci‐fication is conducive to protecting maternal and infant and reducing the adverse pregnancy outcomes .
