A meta-analysis of esophagectomy：the comparative study of Ivor-Lewis operation and Sweet operation
10.3760/cma.j.issn.1671-0274.2014.09.012
- VernacularTitle:食管癌Ivor-Lewis术式与Sweet术式比较研究的Meta分析
- Author:
Hong ZHANG
1
;
Jian WANG
;
Wenchen WANG
;
Lin ZHOU
;
Jiakuan CHEN
;
Bo YANG
;
Yanmin XIA
;
Tao JIANG
Author Information
1. 第四军医大学唐都医院胸外科
- Keywords:
Esophageal neoplasms;
Esophagectomy;
Ivor-Lewis operation;
Sweet operation;
Meta analysis
- From:
Chinese Journal of Gastrointestinal Surgery
2014;(9):892-897
- CountryChina
- Language:Chinese
-
Abstract:
Objective Investigate the best surgical resection of esophageal cancer by comparing the efficacy and safety between Ivor-Lewis esophagectomy and Sweet esophagectomy. Methods The relevant literatures comparing Ivor-Lewis esophagectomy with Sweet esophagectomy were searched through PubMed, Embase, the Cochrane Library, Google scholar, CNKI, CBM, VIP, WanFang Data. RevMan 5.2 software was used for data analysis. Results A total of 4106 patients in 15 studies were reviewed and the data were pooled for analysis. Meta-analysis showed that, compared with the Sweet group, Ivor-Lewis operative time was significantly longer (pooled mean difference=57.40; 95%CI:42.43 to 72.38;P=0.000), operative bleeding was significantly higher (pooled mean difference=28.39, 95%CI:4.06 to 52.72, P=0.02); the number of lymph node dissection significantly more (pooled mean difference=4.19, 95%CI:3.06 to 5.32, P=0.000); No significant difference was present in hospital stay, vocal cord paralysis, chylous leakage, pulmonary complications, anastomotic leakage (all P>0.05). The 5-year survival between the two groups showed no significant difference (P =0.52). Conclutions The two kinds of operation have the same long term effect. Compared with Ivor-Lewis operation, Sweet operation is easier to perform, less time consuming and more tolerable. Ivor-Lewis operation can dissect more lymph nodes than Sweet operation , without increased complications.
