Value of Brain Natriuretic Peptide for the Diagnosis and Treatment of Chronic Left Heart Failure and Cor Pulmonale
- VernacularTitle:脑钠肽在慢性左心衰竭与肺源性心脏病的诊断及治疗中的价值
- Author:
Lina LOU
1
;
Lian CHEN
;
Jingyuan SHEN
;
Lin CAO
;
Qi NI
;
Fang CHEN
Author Information
1. 上海市第二人民医院心内科
- Keywords:
Brain natriuretic peptide;
Chronic congestive heart failure;
Cor pulmonale;
Differential diagnosis;
Therapeutic effect assessment
- From:
Chinese Journal of Clinical Medicine
2015;(2):186-188
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the variation of plasma braln natriuretic peptide(BNP) and its value for diagnosis and treatment in patients with hypertension accompanied by chronic left heart fallure or chronic obstructive pulmonary disease (COPD) accompanied by cor pulmonale(CP) .Methods:A total of 36 patients with hypertension accompanied by chronic left heart fallure and 34 patients with COPD accompanied by CP ,who were admitted to Shanghal Second People’s Hospital from Nov 2010 to Nov 2013 ,were enrolled as study subjects .Meanwhile ,30 normal control were enrolled .Quantitative detection of plasma BNP level was done in each group before and after the treatment .Results:The levels of plasma BNP in the hypertension accompanied by chronic left heart fallure group and the COPD accompanied by CP group before the treatment were higher than that in the control group(P<0 .05) .The levels of plasma BNP in the hypertension accompanied by chronic left heart fallure group was higher than that in the COPD accompanied by CP group before the treatment(P< 0 .05) .After the treatment ,the levels of plasma BNP in both the hypertension accompanied by chronic left heart fallure group and the COPD accompanied by CP group decreased (P<0 .05) .The level of plasma BNP in the hypertension accompanied by chronic left heart fallure group was higher than that in the COPD accompanied by CP group after the treatment(P<0 .05) .Conclusions:BNP can be used as the index for differential diagnosis and therapeutic effect assessment of CP and chronic left heart fallure .
