The Effect of Succinylcholine on the Intracranial Pressure in Cats.
10.4097/kjae.1990.23.2.187
- Author:
Sae Jin CHOI
1
;
Won Hyung LEE
Author Information
1. Department of Anesthesiology, College of Mediciene, Chungnam University, Daejon, Korea.
- Publication Type:Original Article
- Keywords:
Intracranial pressure;
Succinylcholine;
Vecuronium;
d-tubocurarine
- MeSH:
Anesthesia;
Animals;
Cats*;
Intracranial Pressure*;
Succinylcholine*;
Tubocurarine;
Urethane;
Vecuronium Bromide
- From:Korean Journal of Anesthesiology
1990;23(2):187-199
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Succinylcholine (1.5mg/kg) without pretreatment, or succinylcholine (1.5mg/kg) with pretreatment by vecuronium (0.015 mg/kg, 0.045 mg/kg, 0.15 mg/kg) or d-tubocurarine (0.1 mg/kg, 0. 3 mg/ kg, 1mg/kg) was given to cats of the same genus (body weight 2.5-3.5kg) under subcutaneous urethane anesthesia to determine the effect of the intracrainal pressure increase in each method. The results are summarized as follows: 1) The intracranial pressure was significantly increased (0.005< p< 0.01)with the administration of succinylcholine(1.5mg/kg). 2)The intracranial pressure was not increased with the administration of vecuronium. 3)As the dosage of d-tubocuraine administration increased, the intracranial pressure was increased. 4)The increase of the intracranial pressure by succinylcholine was depressed dose-dependently by vecuronium pretreament. 5)The increase of the intracranial pressure by succinylcholine was depressed by d-tubocurarine(0.3mg/kg)pretreatment.
