Effect Evaluation of Dezocine Preemptive Analgesia on Infraclavicular Brachial Plexus Block
- VernacularTitle:地佐辛超前镇痛用于锁骨下臂丛神经阻滞的效果评价
- Author:
Dan-Dan DANG
1
;
Zhi XIE
;
Xuehua CHE
Author Information
1. 复旦大学附属华山医院麻醉科
- Keywords:
Dezocine;
Preemptive analgesia;
Infraclavicular brachial plexus block
- From:
Chinese Journal of Clinical Medicine
2014;(6):668-670
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the effect of dezocine preemptive analgesia on infraclavicular brachial plexus block and the im-pact of it on postoperative analgesia.Methods:Sixty patients,who were classified by American Society of Anesthesiologists (ASA)criteria as classⅠ-Ⅱ and underwent infraclavicular brachial plexus block,were divided randomly into three groups, with 20 cases in each group.In Group A,5 mg dezocine was combined with local anesthetics(20 mL 0.375 % ropivacaine,15 mL 1% lidocaine and 1mL 1∶200 000 epinephrine)for infraclavicular brachial plexus block;in Group B,5mg dezocine was in-travenously injected 15 minutes before the operation and then the same local anesthetics were used;in Group C,infraclavicular brachial plexus block was performed only with the same local anesthetics.The onset time of anesthesia and the operation time, the visual analogue scale (VAS)at 1 h after anesthesia and 8,12,24,36,48 h after operation and the postoperative analgesia time(the time from the end point of operation to the time point when VAS>3),as well as the side effects were recorded.Re-sults:The onset time of anesthesia in Group A were shorter than that in Group B and C(P <0.05).The VAS at 8 h after operation in Group A and B were significantly lower than that in Group C(P <0.05).The VAS at postoperative 12 and 24 h in Group A were significantly lower than those in Group B and C.There was no statistically significant difference in VAS score at 1 h after anesthesia and at 4,36,48 h after operation among the three groups(P >0.05).The analgesia duration was gradually decreased in Group A ,B and C(P <0.05).There was no statistically significant difference between Group A and B in the in-cidence of side effects.Conclusions:The dezocine preemptive analgesia has exact effect.It could prolong the duration of posto-perative analgesia and has few side effects.
