Value of the Detection of Fractional Exhaled Nitric Oxide in the Diagnosis of Bronchial Asthma and Chronic Obstructive Pulmonary Disease
- VernacularTitle:呼出气一氧化氮检测在支气管哮喘和慢性阻塞性肺疾病诊断中的价值
- Author:
Qiong WANG
1
;
Yunping HUANG
;
Chao GUAN
Author Information
1. 上海市徐汇区中心医院呼吸内科
- Keywords:
Chronic obstructive pulmonary disease;
Asthma;
Healthy population;
Fractional exhaled nitric oxide
- From:
Chinese Journal of Clinical Medicine
2014;(6):654-655
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the value of fractional exhaled nitric oxide(FeNO)in the diagnosis of bronchial asthma and chronic obstructive pulmonary disease(COPD).Methods:A hundred and twenty patients with COPD,120 patients with asthma and 120 healthy volunteers were enrolled in this study.FeNO value was compared among the three groups.Results:FeNO value in patients with COPD,patients with asthma,healthy volunteers were (25.8± 15.6)ppb,(64.1 ±51.8)ppb,(18.8± 7.3)ppb,respectively.There was significant differences between the patients with COPD or asthma and the healthy volunteers (P <0.05),and there was significant difference between the patients with COPD and the patients with asthma(P <0.01). There was no significant difference in age,height,weight,and other general information among the three groups.There was no linear correlation between FeNO value and age,height,weight,body mass index,forced expiratory volume in the first second (FEVI)and FEVI to forced vital capacity(FEVI/FVC).Conclusions:The measured value of FeNO in patients with COPD and asthma are higher than that of healthy volunteers.There is no linear correlation between the measured value of FeNO and other values such as FEVI and FEVI/FVC,etc.The reason may be small sample size in this study.
