Influence of Folic Acid on Helicobacter Pylori-Negative Patients with Chronic Atrophic Gastritis
- VernacularTitle:叶酸治疗幽门螺旋杆菌阴性慢性萎缩性胃炎的疗效
- Author:
Yiqun LI
1
;
Jianqun XIE
;
Yuping GONG
;
Yujiao SUN
Author Information
1. 上海中医药大学龙华医院脾胃病研究所
- Keywords:
Chronic atrophic gastritis;
Helicobacter pylori;
Folic acid
- From:
Chinese Journal of Clinical Medicine
2014;(5):523-525
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the effect of folic acid on helicobacter pylori (HP)-negative patients with chronic atrophic gastritis (CAG).Methods:Eighty HP-negative CAG patients were randomly divided into folic acid treatment group (folic acid group)and placebo treatment group (control group),according to different therapy methods,with 40 cases in each group.The course of treatment was 12 weeks.The clinical symptom scores,gastroscopic scores and histopathological scores were com-pared between the two groups.Results:The clinical symptom scores,gastroscopic scores and histopathological scores in folic acid group were significantly decreased after treatment (P <0.05).No statistical significant differences were found in those scores before and after treatment in the control group (P >0.05).After treatment,the scores in folic acid group were signifi-cantly lower than those in the control group (P <0.05).Conclusions:Folic acid can effectively improve the clinical symptoms and pathological changes of HP-negative patients with CAG.
