Effect and Mechanism of Gingko Biloba Extract in the Treatment of Acute Cerebral Infarction
- VernacularTitle:银杏叶提取物治疗急性脑梗死的疗效分析
- Author:
Chenling
1
;
YAO CHENGGUO
Author Information
1. 复旦大学附属中山医院急诊科
- Keywords:
Gingko biloba;
Acute cerebral infarction;
Treatment effect
- From:
Chinese Journal of Clinical Medicine
2014;(5):520-522,525
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyse the effect and machanism of gingko biloba extract in the treatment of acute cerebral infarc-tion.Methods:Forty-four patients diagnosed as acute cerebral infarction were randomly divided into the control group (n=21) and the test group (n=23).Patients in the control group took aspirin,cytidine diphosphate choline and other conventional med-icines,while the patients in the test group received gingko biloba extract capsules combined with the medicine which used in the control group.The parameters measured during the study were MESSS score,Barthel Index,outcomes,and high-sensitivity C-reaction protein(hs-CRP),superoxide dismutase(SOD),malondialdehyde(MDA),endothelin-1(ET-1),thromboxane B2(TXB2) levels.Results:Compared with the control group,the MESSS score,Barthel Index and hs-CRP level in the test group were not improved(P >0.05),but the total clinical effects and the SOD,MDA,ET-1,TXB2 levels were obviously improved(P <0.05). Conclusions:Via increasing the SOD levels and decreasing the MDA,ET-1,TXB2 levels,the treatment of gingko biloba extract combined with aspirin and cytidine diphosphate choline in acute cerebral infarction is effective and safe.
