Efficacy of Zhenjujiangya Tablet Combined with Valsartan in the Treatment of Hypertension (Upper Hyperac-tivity of Liver Yang) Patients
- VernacularTitle:珍菊降压片联合缬沙坦治疗原发性高血压（肝阳上亢证）患者的疗效观察
- Author:
Qiong MENG
1
;
Hao HUANG
;
Jinpei LIN
;
Xiaodong FU
Author Information
1. 复旦大学附属华山医院永和分院内科
- Keywords:
Hypertension;
Zhenjujiangya tablet;
Valsartan;
Curative effect
- From:
Chinese Journal of Clinical Medicine
2014;(3):348-350
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To study the efficacy of Zhenjujiangya tablet combined with angiotensin Ⅱ receptor blocker (ARB) val-sartan in the treatment of hypertension (upper hyperactivity of liver yang ) .Methods :A total of 60 patients with primary hyper-tension syndrome (upper hyperactivity of liver yang ) were randomly divided into treatment group (Zhenjujiangya tablet + val-sartan ,n=32) and control group (hydrochlorothiazide + valsartan ,n=28) .At 8 weeks after the treatment ,dynamic blood pressure ,blood pressure variability and TCM symptom score were observed .Results:After treatment ,compared with the con-trol group ,SBP ,d-SBP ,n-SBP in the treatment group were significantly lower (P<0 .05) ,whereas DBP ,d-DBP ,n-DBP had no significant difference (P<0 .05) .The blood pressure variability d-SBPV and n-SBPV in the treatment group were signifi-cantly lower than those in the control group (P<0 .01) ,but d-DBPV ,n-DBPV had no significant difference between the two groups (P>0 .05) .In the treatment group ,TCM symptoms(dizziness ,headache ,irritability) scores were significantly lower (P<0 .05) than those in the control group ,but limb symptoms integral differences had no difference between the two groups (P>0 .05) .Conclusions:Zhenjujiangya tablet in combination with valsartan therapy in patients with hypertension (upper hyperactivity of liver yang ) can not only effectively reduce the blood pressure and improve blood pressure variability ,but also improve the clinical symptoms of patients .
