Evaluation of Lidocaine Combined with Tramadol for Preemptive Analgesia
- VernacularTitle:利多卡因联合曲马多超前镇痛的效果观察
- Author:
Jing XUE
1
;
Hongmei JIANG
;
Xiaoru WU
Author Information
1. 甘肃省庆阳市人民医院麻醉科
- Keywords:
Lidocaine;
T ramadol;
Preemptive analgesia;
Drug combination
- From:
Chinese Journal of Clinical Medicine
2014;(3):319-321
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To analyze the effect and security of lidocaine combined with tramadol for preemptive analgesia .Meth-ods:A totle of 90 patients undergoing laparoscopic cholangiotectomy under total infusion venus anesthesia (TIVA) were divided into Group T1 ,Group T2 and Group C ,with 30 patients in each group .Before and after the operation ,the patients in Group T1 received intravenous tramadol 100 mg ;the patients in Group T2 received intravenous lidocaine 50 mg and tramadol 50 mg ;the patients in Group C received saline injection .The awakening time ,alertness/sedation (OAA/S) scale ,visual analoue scale (VAS) ,and the untoward effects of patients after operation among the 3 groups were compared .Results:The postoperative a-wakening time of patients in 3 groups had no statistical difference ,and the OAA/S score at postoperative15 min in Group T1was higher than those in Group T2 and Group C (P<0 .05) .The VAS scores at 0 .5、1、2 、4、6、12 h after the operation in Group T1 and Group T2 were lower than those in Group C (P<0 .05) ,but those in Group T1 and Group T2 had no statistical diffe-rences .The blood pressure and heart rate of patients in Group T 2 were more stable than those in Group T1 and Group C .Con-clusions:Lidocaine combined with tramadol intravenously injected shows definite preemptive analgesia effects and stable anes-thesia recovery ,and it is better than tramadol alone .
