Detection and Analysis on Gene Subtypes of Cervical Human Papilloma Virus Infection in Pregnant and Non-Pregnant Women
- VernacularTitle:妊娠及非妊娠妇女宫颈感染人乳头瘤病毒的基因亚型检测及分析
- Author:
Xinzhong NG WA
1
;
Junhong ZHAO
Author Information
1. 复旦大学附属金山医院妇产科
- Keywords:
Cervical;
Human papilloma virus;
Gene subtypes;
Pregnancy;
Non-pregnancy
- From:
Chinese Journal of Clinical Medicine
2014;(3):288-290
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To investigate the gene subtypes of cervical human papilloma virus (HPV) infection in pregnant and non-pregnant women .Methods :From February 2012 to May 2013 ,cervical epithelial cells in 684 women of childbearing age (non-pregnant women) and 857 pregnant women in Jinshan Hospital ,Fudan University were collected .Polymerase chain reaction (PCR) and gene-chip technique were used to detect HPV gene subtype .Results :A total of 195 positive results were found in non-pregnant women with the HPV infection rate of 28 .5% .The predominant types of HPV infection were type 43 ,16 and 58 .A total of 102 positive results were found in pregnant women with the HPV infection rate of 11 .9% .The predominant types of HPV infection were type 43 ,16 and 58 .The infection rates of pregnant women in less than 30 years of age ,30 to 40 years old ,more than 40 year old were 10 .9% ,15 .1% and 30% ,respectively .The infection rates of non-pregnant women in less than 30 years ,30 to 40 years old ,more than 40 year old were 25 .3% ,25 .2% and 32 .2% ,respectively .Conclusions :The HPV infection rate of pregnant women was lower than that of non-pregnant women .The main HPV infection subtypes of the pregnant women and the non-pregnant women were the same .HPV43 ,16 and 58 were the predominant subtypes in this hospi-tal .The infection rate of non-pregnant women increased significantly in accordonce with age .
