Efficacy Comparison of Different Routes of Intracoronary Verapamil on No-Reflow Phenomenon during Emer-gency Percutaneous Coronary Intervention
- VernacularTitle:经不同途径冠脉内应用异搏定对急诊冠脉介入治疗术中无复流现象的疗效比较
- Author:
Dong NG HUA
1
;
Juying QIAN
;
Lei GE
;
Qibing WANG
;
Bing FAN
;
Yan YAN
;
Feng ZHANG
;
Jianying MA
;
Kang YAO
;
Junbo GE
Author Information
1. 复旦大学附属中山医院心内科
- Keywords:
Percutaneous coronary intervention;
No-reflow;
Verapamil
- From:
Chinese Journal of Clinical Medicine
2014;(3):279-281
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To explore the efficacy difference of two different routes of intracoronary verapamil on no-reflow phe-nomenon during primary percutaneous coronary intervention (PCI) in patients with acute ST-segment elevation myocardial in-farction (STEMI) .Methods :From January 2009 to December 2012 ,141 STEMI patients with no-reflow phenomenon during e-mergency PCI who received the manual intracoronary bolus infusion of verapamil were selected .According to the routes of in-tracoronary verapamil ,patients were divided into guiding catheter group (n=67) and selective catheter group (n=74) .The coronary perfusion level ,the ECG ST-segment resolution ,left ventricular ejection fraction (LVEF) and major adverse cardiac events in 30 days post-PCI were compared .Results:There were no statistically significant differences in general datum of the two groups and the average dose of intracoronary infusion verapamil (P>0 .05) .The level of cTFC in the the selective catheter group was significantly lower than that in the guiding catheter group (P<0 .05) .More patients restored the TIMI-3 flow after drug infusion in selective catheter group than guiding catheter group (P<0 .05) .The proportion of complete ST-segment reso-lution after PCI in the selective catheter group was significantly higher than that in guiding catheter group (P<0 .05) .No sta-tistically significant differences were found in LVEF and incidence of major adverse cardiac events during 30 days between the two groups (both P>0 .05) .Conclusions :The intracoronary verapamil through selective catheter can reverse no-reflow phe-nomenon more effectively than through guiding catheter during emegency PCI for STEMI .
