Clinical observation and experimental study of acute hemolysis following copper needle electrothrombosis for treating hemangioma
10.3760/j.issn:1009-4598.2001.01.011
- VernacularTitle:铜针通电治疗血管瘤并发急性溶血
- Author:
Heping XU
1
;
Yaoming XIAO
;
Yanzhen ZHOU
Author Information
1. Zhangzhou Municipal Hospital
- From:
Chinese Journal of Plastic Surgery
2001;17(1):37-39
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the pathogenesis of acute intravascular hemolysis following copper needle electrothrombosis for treating a huge cavernous hemangioma. Methods (1) The full course of severe intravascular hemolysis in a patient with huge cavemous hemangioma treated by copper needle electrontrombosis was observed. (2)In vitro experiment, a copper needle, an iron needle and a stainlss-steel needle were put in citrated anticoagulant healthy blood specimens respectively. The needles were electrified with 3～6 voltages DC for 30 minutes. Then the free hemoglobin of the specimens was tested before,during and after electrfication. The red cell morphology was observed under a light microscope. Results Severe intravascular hemolysis occurred in twice treatments with copper needle electrothrombosis. In vitro experiment showed that erythroclasis occurred after needle electrifying with obvious increasing of free plasma hemoglobin of the specimens. The higher the voltage and the longer the electrification of the needle, the more severe the hemocytocatheresis. Conclusions Severe intravascular hemolysis may happen during copper needle electrothrombosis for treating huge cavernous hemangioma. Red blood cell injury directly caused by electrification is the main factor of intravascular hemolysis.
