Hemorrhagic Transformation of Ischemic Stroke: Severe Complications of Prosthetic Valve Endocarditis.
10.4070/kcj.2011.41.8.490
- Author:
Jin Sun KIM
1
;
Woo In YANG
;
Chi Young SHIM
;
Jong Won HA
;
Namsik CHUNG
;
Hyuk Jae CHANG
Author Information
1. Department of Internal Medicine, Yonsei University College of Medicine, Seoul, Korea. hjchang@yuhs.ac
- Publication Type:Case Report
- Keywords:
Heart valve prosthesis;
Endocarditis;
Stroke;
Cerebral hemorrhage;
Anticoagulants
- MeSH:
Anticoagulants;
Cerebral Hemorrhage;
Endocarditis;
Heart Valve Prosthesis;
Humans;
Prothrombin Time;
Retrospective Studies;
Stroke
- From:Korean Circulation Journal
2011;41(8):490-493
- CountryRepublic of Korea
- Language:English
-
Abstract:
Ischemic stroke is a common complication of infective endocarditis (IE), occurring in 20-40% of left side IE cases. In these subsets, anticoagulation therapy may provoke hemorrhagic transformation (HT) of ischemic stroke, and complications of this magnitude deteriorate the clinical course for IE patients. However, in cases of IE complicated with a mechanical prosthetic valve, the physician can be concerned over the maintenance of anticoagulation due to the risk of thrombotic complication. According to our retrospective review, HT of ischemic stroke in prosthetic valve endocarditis occurred 13.8% (4/29) of the time in a variety of situations. Some of these even arose in patients with a subtherapeutic range of prothrombin time.
