Research Progresses of Circulating Tumor Cells in Diagnosis and Treatment of Early Lung Cancer
10.3779/j.issn.1009-3419.2017.10.07
- VernacularTitle:循环肿瘤细胞在早期肺癌诊疗中的研究进展
- Author:
DUAN XINCHUN
1
;
LIU ZHIDONG
;
XU SHAOFA
Author Information
1. 首都医科大学附属北京胸科医院胸外二科
- Keywords:
Circulating tumor cells;
Liquid biopsy;
Small pulmonary nodules;
Lung neoplasm;
Diagnosis
- From:
Chinese Journal of Lung Cancer
2017;20(10):703-709
- CountryChina
- Language:Chinese
-
Abstract:
As one of the important liquid biopsies, circulating tumor cells (CTCs) shows more and more clinical values in the treatment of lung cancer such as diagnostic screening, treatment evaluation, postoperative monitoring, and prog-nosis predicting etc.A large number of small pulmonary nodules patients are detected when screening the high risk population of lung cancer. However, small lung nodules are not equal to lung cancer, and 90%-95% of them are benign lesion, therefore, to accurately and correctly differentiate whether it is benign or malignant when patients firstly detected and treat a small pulmo-nary nodule is become a new opportunity and challenge for clinician. With the improvement of CTCs detection technology, whether it will play an important role in early differential diagnosis of lung cancer. And whether it will have clinical significance to early lung cancer surgery operations. These require further researches and explorations so as to achieve clinical transforma-tion in the future.
