Multi-omics prediction of lymph node metastasis status in breast cancer
10.3760/cma.j.cn112152-20230822-00093
- VernacularTitle:乳腺癌区域淋巴结转移状态的多组学预测
- Author:
Ying JIN
1
;
Wei WANG
;
Jianbin LI
Author Information
1. 山东第一医科大学（山东省医学科学院），济南250117
- Keywords:
Breast neoplasms;
Lymph node metastasis;
Multi-omics;
Forecasting
- From:
Chinese Journal of Oncology
2024;46(5):391-398
- CountryChina
- Language:Chinese
-
Abstract:
Lymph node metastasis status stands as a pivotal prognostic indicator in forecasting the outlook for breast cancer patients. Consequently, precise evaluation of this status holds paramount importance in the staging, treatment, and prognosis of breast cancer. The utilization of radiomics, genomics, proteomics, transcriptomics, and histopathology methodologies has notably enhanced the precision of lymph node metastasis status prediction in breast cancer. This review provides an overview of recent advancements in omics-based lymph node metastasis prediction for breast cancer, elucidating the significance of various omics prediction models and integrated multi-omics models in this predictive endeavor. The overarching goal is to augment the accuracy of preoperative lymph node metastasis status prediction in breast cancer, thereby aiding clinicians in the selection of efficacious personalized treatment strategies, while concurrently averting undertreatment of patients with a heightened risk of metastasis.
