Clinical Characteristics of Lung Cancer with Pancreatic Metastases
10.3779/j.issn.1009-3419.2017.08.02
- VernacularTitle:肺癌胰腺转移的临床特点及预后分析
- Author:
DUAN JIANCHUN
1
;
WAN RUI
;
SHEN JIANQIN
;
LIU XUYI
;
WANG JIE
;
ZHAO JUN
;
WU MEINA
;
YANG LU
;
AN TONGTONG
;
GUO QINGZHI
Author Information
1. 中国医学科学院肿瘤医院肿瘤内科
- Keywords:
Lung neoplasms;
Pancreatic metastasis;
Pancreatitis;
Multimodality therapy
- From:
Chinese Journal of Lung Cancer
2017;20(8):511-515
- CountryChina
- Language:Chinese
-
Abstract:
Background and objective Lacking of typical symptoms, more than 70% of patients with lung cancer are diagnosed as advanced-stage disease. Patients suffer from solid organs metastasis with different clinical features and prog-nosis. With development of new technology, more and more lung cancer patients are diagnosed with pancreatic metastasis. The aim of this study was to investigate clinicopathologic and survival difference by retrospective analysis among lung cancer patients with pancreatic metastases.Methods Of the patients with lung cancer diagnosed by pathology and thorough staging evaluation and treated at Beijing Cancer Hospital with long follow-up during July 1996 and June 2017, 35 cases had pancreatic metastases.Results There were 28 cases diagnosed as small cell lung cancer, 3 cases diagnosed as adenocarcinoma and 4 cases diagnosed as squamous cell carcinoma. There were 15 cases with pancreatic metastases in head of pancreas and 20 cases in body and tail of pancreas, 23 cases presented with isolated metastasis and 12 cases with multiple metastases. Pathological type was prognostic factor for lung cancer patients with pancreatic metastases.Conclusion Pancreatic metastases represents an uncommon site of extrathoracic spread of disease for part of patients with advanced lung cancer. Lung cancer with pancreatic metastases should be treated by combined therapy, especially by systemic chemotherapy. Pathological type was prognostic fac-tor for lung cancer patients with pancreatic metastases.
