Clinical Value of Cell Block in the Diagnosis of Malignant Pleural Effusion
10.3779/j.issn.1009-3419.2017.06.05
- VernacularTitle:胸腔积液沉淀物在恶性胸腔积液诊断中的临床应用价值
- Author:
WANG XINTONG
1
;
CHENG FANGYUAN
;
ZHONG DIANSHENG
;
ZHANG LISHA
;
MENG FANLU
;
SHAO YI
;
YU TAO
Author Information
1. 天津医科大学总医院肿瘤科
- Keywords:
Malignant pleural effusion;
Natural sedimentation;
Plasma coagulation method;
Imunohistochemical staining;
Clinical value
- From:
Chinese Journal of Lung Cancer
2017;20(6):395-401
- CountryChina
- Language:Chinese
-
Abstract:
Background and objective Malignant pleural effusion (MPE) is due tumor which arises from the me-sothelium or metastases from tumor origniating other sites. Generally, the prognosis of MPE is poor, in the premise of reduc-ing the pain of patients, as soon as possible make clear the property of pleural effusion and cause of the disesease, rightly and quickly, providing effective information for subsequent treatment. Methods The cell block of 103 patients by using natural sedimentation or plasma coagulation method combined with HE staining and immunohistochemical staining method maked clear diagnosis and compared with other methods. Results 90 patients were diagnosed by cell block section from 103 patients who had MPE (diagnostic rate 87.4%); 32 cases were diagnosed by cell block section only, 74 cases pointed out that the patho-logical type , 23 cases even pointed out the primary lesions; 71 cases examined other invasive methods at the same time, the di-agnostic rate was 87.3% and 81.7%; the detection rate of cell block section and cytological smear in detecting malignant tumor cells was 86.7%and 44.0% respectively. Conclusion Cell block can not only increase the diagnosis, in contrast to cytological smear, and own the same diagnostic rate compared with other invasive methods, but also can confirm pathological type and primary lesion; especially, for other invasive methods, cell block method is a preferable complementary method, and that cell block method maybe the only way for some patients.
