Distant Metastasis and Survival Outcomes after Computed Tomography-guided Needle Biopsy in Stage -Ⅱ Non-small Cell Lung Cancer
10.3779/j.issn.1009-3419.2017.03.07
- VernacularTitle:CT引导下穿刺活检对I期-II期非小细胞肺癌远处转移和生存的影响
- Author:
FAN JINGLI
1
;
ZHAI KEKE
;
REN TINGTING
;
FENG XIAO
;
SUI LIN
;
HU JING
;
MENG QINGWEI
Author Information
1. 哈尔滨医科大学附属肿瘤医院肿瘤内科
- Keywords:
Lung neoplasms;
Computed tomography-guided percutaneous needle biopsy;
Biopsy;
Distant metas-tasis;
Survival
- From:
Chinese Journal of Lung Cancer
2017;20(3):187-191
- CountryChina
- Language:Chinese
-
Abstract:
Background and objectiveComputed tomography-guided needle biopsy (CTNB) is a well-established and commonly used technique for diagnosing pulmonary nodules with high accuracy and safety. Needle-tract implantation after CTNB has been reported in various reports. The aim of this study is to evaluate whether preoperative CTNB affected the distant metastasis and overall survival in pathological stage I-II lung cancer patients.Methods A total of 1,234 patients with pathological stage I-II non-small cell lung cancer were collected. 113 patients received preoperative CTNB, and 1,121 patients did not receive any biopsy before surgical resection. Propensity score-matching method was adopted to balance observed co-variates between two groups, 113 pairs were matched.Cox regression analysis andKaplan-Meier estimates were used to process survival analysis.Results Distant metastasis free survival (DMFS) was significantly poorer in the preoperative CTNB group than in the non-biopsy group (P=0.032). But there was no difference in the overall survival between the two groups (P=0.086). Conclusion CTNB increased the risk of distant metastasis, not increasing the risk of mortality.
