Treatment of Advanced Squamous Cell Lung Cancer
10.3779/j.issn.1009-3419.2016.10.10
- VernacularTitle:晚期肺鳞癌的治疗
- Author:
ZHU YIXIANG
1
;
XING PUYUAN
;
LI JUNLING
Author Information
1. 国家癌症中心/中国医学科学院北京协和医学院肿瘤医院
- Keywords:
Lung neoplasms;
Chemotherapy;
Targeted therapy
- From:
Chinese Journal of Lung Cancer
2016;19(10):687-691
- CountryChina
- Language:Chinese
-
Abstract:
Lung cancer is the deadliest cancer in the worldwide. Non-small cell lung cancer (NSCLC) accounts for 85% of lung tumor diagnoses. Squamous cell lung cancer (SQCLC) is a common pathological type, almost 20%-30% of NSCLC. Surgery, chemotherapy, and molecular targeted therapies are the mainstay of treatment for patients with SQCLC. But most patients are diagnosed at advanced stage so that they miss the chance of operation. While noteworthy outcomes have im-proved with adenocarcinoma of lung with epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs), a thera-peutic plateau for advanced squamous cell lung cancer patients are still not solved. EGFR-TKIs are unsuitable for or mostly in-effective in advanced SQCLC. Patients with advanced SQCLC ramain treated with platinum based chemotherapy. hTis reciew systematicly describe the treatment of squamous cell carcinoma of the lung.
