Whole Brain Irradiation and Hypo-fractionation Radiotherapy for the Metastases in Non-small Cell Lung Cancer
10.3779/j.issn.1009-3419.2016.04.08
- VernacularTitle:非小细胞肺癌脑转移全脑及病灶局部大分割放射治疗
- Author:
GU XINGTING
1
;
ZHAO YAQIN
;
XU FENG
Author Information
1. 四川大学华西医院肿瘤中心
- Keywords:
Lung neoplasms;
Brain metastasis;
Whole brain radiotherapy;
Treatment side effects
- From:
Chinese Journal of Lung Cancer
2016;19(4):224-229
- CountryChina
- Language:Chinese
-
Abstract:
Up to 40%non-small cell lung cancer patients developed brain metastasis during progression. Multiple brain metastases are common in non-small cell lung cancer. hTe prognosis of brain metastasis is poor with median survival of less than 1 year. Radio therapy for brain metastases has gradually developed from whole brain radiotherapy (WBRT) to various radiation strategies. WBRT, surgery+WBRT, stereotactic radiotherapy+WBRT or WBRT with simultaneous integrated boost (SIB), etc. have better overall survival than those untreated patients. hTe damage of the cognitive function from WBRT has been realized recently, however, options of radiation strategies for long expected survival patients remain controversial. hTis paper will discuss different WBRT strategies and treatment side effects of non-small cell lung cancer with brain metastases.
