Application value of a Nomogram model established on clinical and ultrasound features in modifying classification results of the Chinese Thyroid Imaging Reporting and Data System by ultrasound physicians
- VernacularTitle:基于临床与超声特征构建的列线图模型在超声医师修饰甲状腺中国(超声)甲状腺影像报告和数据系统分类结果中的应用价值
- Author:
Yinhua ZHAO
1
;
Yu LIANG
;
Yunhan WANG
;
Li YANG
;
Tong XU
;
Erxi FAN
;
Xuan LI
Author Information
- Keywords: thyroid nodules; Nomogram; ultrasound physicians; the Chinese Thyroid Ima-ging Reporting and Data System; modification; value
- From: Journal of Clinical Medicine in Practice 2024;28(11):18-22,28
- CountryChina
- Language:Chinese
- Abstract: Objective To analyze the application value of a Nomogram model established on clinical and ultrasound features of thyroid in modifying classification results of the Chinese Thyroid Im-aging Reporting and Data System(C-TI-RADS)by ultrasound physicians.Methods The clinico-pathological ultrasound materials of patients with surgical resection for thyroid nodules in Sichuan Pro-vincial People's Hospital(training set,n=841)and Sichuan Mianyang 404 Hospital(external vali-dation set,n=295)from January 2021 to December 2022 were retrospectively analyzed,and preop-erative thyroid ultrasound was used to classify thyroid nodules by C-TI-RADS.Univariate and Multi-variate Logistic regression analyses were used to screen independent predictors in the training set and a Nomogram model was constructed,and Bootstrap resampling was used for internal validation;ultrasound physicians in Sichuan Mianyang 404 Hospital were charged in external verification based on this Nomogram model.Receiver operating characteristic(ROC)curve and calibration curve were drawn to evaluate the efficacy of the model and its clinical value in modifying the classification results by C-TI-RADS.Results Univariate and Multivariate Logistic regression analyses showed that gender,age,maxi-mum diameter of nodules,the number of nodules,ultrasound abnormalities of cervical lymph nodes and C-TI-RADS classification were the independent factors for predicting the modified classification results of C-TI-RADS by ultrasound physicians(P＜0.05).Consistency index of the Nomogram model constructed based on these factors was 0.842(95％CI,0.816 to 0.867),the area under the curve(AUC)was 0.842,sensitivity was 92.9％,specificity was 63.7％,and accuracy was 75.9％.The prediction results of the Nomogram model were in good agreement with the actual situa-tion in both the training set and the external validation set.Conclusion Nomogram model based on clinical and ultrasound features of thyroid shows good predictive accuracy in modifying classification results of C-TI-RADS by ultrasound physicians,which has potential clinical application value.
