Value of Cell Block in the Diagnosis of Malignant Pleural Effusion
10.3779/j.issn.1009-3419.2015.10.09
- VernacularTitle:胸腔积液沉淀物在恶性胸腔积液诊断中的价值
- Author:
CHENG FANGYUAN
1
;
WANG QIAN
;
ZHONG DIANSHENG
Author Information
1. 天津医科大学总医院肿瘤科
- Keywords:
Malignant pleural effusion;
Cell block;
Diagnostic value
- From:
Chinese Journal of Lung Cancer
2015;(10):652-655
- CountryChina
- Language:Chinese
-
Abstract:
Malignant pleural effusion (MPE ) is due tumor which arises from the mesothelium or metastases from tumor origniating other sites. In large, for undiagnosed unilateral pleural effusions, the most frequent and important diagnosis to be established or excluded is malignancy. Cell block is prepared from residual lfuid which is centrifuged or is naturally sedi-menting to obtain clots at the bottom of the container. hTe cell block technique is simple, relatively non-invasive, reproducible and has a high yield for malignant plerual effusion. It plays an important role in the diagnosis, guiding the treatment of maligant pleural effusion. Herein, we summarize the technologys which make the cell block, the differential diagnostic value when multiple sections of the cell block are processed for immunhistochemistry, advantages in the diagnosis of malignant pleural ef-fusion, the clinical value of gene screening in cell block. hTe aim of this article is to discuss the value of cell block in diagnosis of maligant pleural effusion.
