Progress of Postoperative Adjuvant Chemotherapy in Stage I Non-small Cell Lung Cancer
10.3779/j.issn.1009-3419.2015.06.08
- VernacularTitle:I期非小细胞肺癌术后辅助化疗的研究进展
- Author:
LIU BO
1
;
DING FENGXIA
;
YANG SHUANGQIANG
Author Information
1. 重庆医科大学附属第一医院胸心外科
- Keywords:
Lung neoplasms;
Stage I;
Postoperative adjuvant chemotherapy
- From:
Chinese Journal of Lung Cancer
2015;(6):374-380
- CountryChina
- Language:Chinese
-
Abstract:
hTe morbidity and mortality of lung cancer rank the ifrst place among all the malignant tumor. Accord-ing to the histopathological characteristics, lung cancer is divided into non-small cell lung cancer (NSCLC) and small cell lung cancer. Only 20% patients diagnosed with NSCLC have the chance for surgery while their 5-yr overall survival is about 30%-60%. hTe therapeutic outcome of surgery alone is not satisfying. Adjuvant chemotherapy atfer surgical resection in stage II-IIIa lung cancer showed effcacy in many randomized clinical trials, but its role in stage I disease remains controversial. hTe choice of appropriate chemotherapy candidates, the selection of chemotherapy regimens and the research progress on bio-marker are mainly discussed in this review.
