A Case of Invasive Pulmonary Aspergillosis in a Patient with Rheumatoid Arthritis Treated with Adalimumab.
10.4078/jrd.2011.18.3.212
- Author:
Jae Hee KIM
1
;
Joong Ki BAE
;
Jae Wan JUN
;
Hyun Sung LEE
;
Hyung Wook JU
;
Ji Seon OH
;
Seung Won CHOI
Author Information
1. Department of Internal Medicine, Ulsan University Hospital, College of Medicine, University of Ulsan, Ulsan, Korea. choisw@uuh.ulsan.kr
- Publication Type:Case Report
- Keywords:
Invasive aspergillosis;
Rheumatoid arthritis;
Tumor necrosis factor-alpha
- MeSH:
Antibodies, Monoclonal, Humanized;
Arthritis, Rheumatoid;
Humans;
Invasive Pulmonary Aspergillosis;
Opportunistic Infections;
Tuberculosis;
Tumor Necrosis Factor-alpha;
Adalimumab
- From:Journal of Rheumatic Diseases
2011;18(3):212-215
- CountryRepublic of Korea
- Language:English
-
Abstract:
We describe a fatal case of invasive pulmonary aspergillosis in a patient with rheumatoid arthritis receiving the TNF-alpha inhibitor, adalimumab. The use of TNF-alpha inhibitor has been associated with an increased risk of infections, including tuberculosis and other opportunistic infections. Physicians should have a high index of suspicion for opportunistic infection that can develop during TNF-alpha inhibitor treatment.