Inlfuence of Thoracoscopic Surgery on Inlfammatory Reaction of the Body for Early Peripheral Lung Cancer Patients
10.3779/j.issn.1009-3419.2014.10.04
- VernacularTitle:胸腔镜早期周围型肺癌根治术对患者术后炎性反应状态的影响
- Author:
LIU YI
1
;
ZHAO HONGLIN
;
LIU JINGHAO
;
WU YI
;
XU SONG
;
LIN GAOYANG
;
CHEN JUN
;
CHEN GANG
;
ZHOU QINGHUA
Author Information
1. 天津医科大学总医院肺部肿瘤外科
- Keywords:
hToracoscopy;
Lung neoplasms;
Inlfammatory reaction;
Lobectomy
- From:
Chinese Journal of Lung Cancer
2014;(10):730-733
- CountryChina
- Language:Chinese
-
Abstract:
Background and objective It has been proven that video assited thoracoscopic surgery (VATS) achieved the same survival rates compared with traditional open chest operation in the treatment of early stage of lung cancer. but it is unclear if there is any difference of body inlfammatory reaction between the two operation. hTe aim of this study is to investigate the changes of inlfammatory state of thoracoscopic radical lobectomy in early peripheral lung cancer patients. Meth-ods Senventy-one early peripheral lung cancer patients who have underwent radical lobectomy were divided into two groups based on the different operation method. hTe VATS group was treated by thoracoscopic lobectomy. hTe thoracotomy group was treated by traditional thoracotomy. hTen the level of serum C-reactive protein (CRP), tumor necrosis factor-α(TNF-α), in-terleukin-6 (IL-6) and IL-10 at 1-day before operation and 3-day, 7-day postoperation were measured and compared between the two groups. Results No signiifcant difference was found in the level of serum CRP, TNF-α, IL-6 and IL-10 before opera-tion. Compared to the thoracotomy group, the level of serum CRP, TNF-α, IL-6 and IL-10 in the VATS group were signiifcant-ly lower atfer operation. Conclusion Compared with thoracotomy lobectomy, thoracoscopic lobectomy for early peripheral lung cancer patients is associated with lower inlfammatory responses .
