Clinical Value of Ultrasound in the Diagnosis of Supraclavicular Lymph Node Metastasis of Primary Lung Cancer
10.3779/j.issn.1009-3419.2014.09.04
- VernacularTitle:锁骨上超声检查提高原发性肺癌N分期的应用价值
- Author:
LIU ZHAO
1
;
CHENG WEN
;
LI PENGFEI
;
SUN YIXIN
;
WANG QIUCHENG
Author Information
1. 哈尔滨医科大学附属肿瘤医院超声科
- Keywords:
Lung neoplasms;
Supraclavicular lymph node;
Ultrasound;
Enhanced CT;
Staging;
Diagnosis
- From:
Chinese Journal of Lung Cancer
2014;(9):663-668
- CountryChina
- Language:Chinese
-
Abstract:
Background and objective Primary lung cancer has been common malignant tumors. Accurate pre-operative N staging can avoid unnecessary surgical operations, and patients with N3 has non-surgical treatment of indica-tions. hTe aim of this study is to investigate the clinical value of ultrasound in the diagnosis of supraclavicular lymph node metastasis and staging of primary lung cancer. Methods We retrospectively analyzed 131 patients who were pathologically diagnosed with lung cancer from October 2012 to November 2013. All patients received ultrasound and contrast-enhanced computed tomograohy (CT) examination of the supraclavicular area, and those who were with positive results underwent ultrasound-guided biopsy. hTe accuracy of the two methods was compared according to their consistency with the patho-logical results. hTe pathological diagnosis was used as the diagnosis standard of lymph node metastasis. Results hTere were 50 cases of patients who were conifrmed supraclavicular lymph node metastasis pathologically in a total of 131 cases of patients with lung cancer. Fitfy-four cases were tested positive by ultrasound, and 50 cases were pathologically proven to be with lymph node metastasis. For comparison, the ratio was 36 out of 41 for contrast-enhanced CT. hTe sensitivity, speciifc-ity, You den's index, the positive predictive value and the negative predictive value of ultrasound (100%, 95.06%, 95.06%, 92.59%, 100%) was signiifcantly higher than that of contrast-enhanced CT (72%, 93.83%, 65.83%, 87.80%, 84.44%). hTe differences of accuracy of the two methods in TNM staging of lung cancer had statistically signiifcance (P<0.01). Conclu-sion Compared with enhanced CT, ultrasound examination has high accuracy, sensitivity and speciifcity for primary su-praclavicular lymph node metastasis in lung cancer, and at the same time can determine the TNM staging of primary lung cancer more accurately.
