Current Status of Translational Research on Functional Dyspepsia.
10.4166/kjg.2016.68.3.132
- Author:
Jae Ho PARK
1
;
Jong Wook KIM
;
Jong Kyu PARK
;
Cheol Min SHIN
;
Kee Wook JUNG
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan, Korea. jung.keewook30@gmail.com
- Publication Type:Review
- Keywords:
Functional dyspepsia;
Translational medical research
- MeSH:
Appetite;
Brain;
Dyspepsia*;
Eating;
Ghrelin;
Immune System;
Magnetic Resonance Imaging;
Mast Cells;
Translational Medical Research*
- From:The Korean Journal of Gastroenterology
2016;68(3):132-137
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Functional dyspepsia (FD) has a diverse pathophysiology and treatment is difficult. Translational research to understand its pathophysiology is underway. Hormonal factors, including ghrelin, seem promising, offering an understanding of appetite and eating. Functional MRI brain study can expand our knowledge of the brain-gut axis. Finally, immune systems research, including mast cells, can help with comprehensive understanding of FD. The clinical approaches based on these translational research projects are necessary to improve understanding of FD, leading to more effective treatment.
