The role of EBUS?TBNA in the systematic evaluation of lymph node staging and resectability analysis in non?small cell lung cancer
10.3760／cma.j.issn.0253?3766.2019.10.013
- VernacularTitle:超声支气管镜引导下经支气管壁针吸活检术在非小细胞肺癌淋巴结系统性评价及可切除性分析中的作用
- Author:
Junyong ZOU
1
;
Weihe ZHAO
;
Jinglu CHEN
;
Xuekui DU
;
Xiaowei HU
;
Zhenyue YE
Author Information
1. 中国科学院大学宁波华美医院呼吸及危重症科315010
- Keywords:
Carcinoma,non?small?cell lung;
Endobronchial ultrasound guided transbronchial needle aspiration;
Systematic evaluation;
Lymph node staging;
Resectability
- From:
Chinese Journal of Oncology
2019;41(10):792-795
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of endobronchial ultrasound guided transbronchial needle aspiration (EBUS?TBNA) in lymph node staging and resectability assessment of patients with non?small cell lung cancer (NSCLC). Methods The clinical data of 154 patients with NSCLC who underwent EBUS?TBNA from March 2015 to December 2018 were collected. All accessible mediastinal and hilar lymph nodes were systematically explored and punctured using EBUS?TBNA. EBUS?TBNA and CT were used for preoperative staging and resectability evaluation.Results The sensitivity, specificity and accuracy of EBUS?TBNA were 94.2%, 100.0% and 96.0%, respectively, while those of CT were 89.9%, 31.8% and 72.0%, respectively.The differences were statistically significant (P＜0.05).The sensitivity, specificity and accuracy of EBUS?TBNA in lymph nodes with short diameter less than 15 mm were 92.4%, 100.0% and 96.0%, respectively, while those of CT were 80.7%, 34.8% and 60.1%, respectively, with statistical differences (P＜0.05). The staging of 62 patients was changed, 27 cases were up?regulated and 35 cases were down?regulated. Among them, 32 cases had been changed to resectable. The evaluating resectability of EBUS?TBNA showed excellent consistency with that of pathological results ( Kappa＝0.95). The sensitivity and specificity were 100.0% and 97.2%, respectively. Conclusion EBUS?TBNA can systemically evaluate the metastatic status of NSCLC patients and improve the accuracy of preoperative lymph node staging and resectability assessment.
