A Case of Myeloid Sarcoma of Intestine.
10.4166/kjg.2016.68.3.148
- Author:
Sung Won LIM
1
;
Hang Lak LEE
;
Kang Nyeong LEE
;
Dae Won JUN
;
In Young KIM
;
Eunjin KIM
;
Hyein AHN
;
Chan Kum PARK
Author Information
1. Department of Internal Medicine, Hanyang University College of Medicine, Seoul, Korea. alwayshang@hanyang.ac.kr
- Publication Type:Case Report
- Keywords:
Sarcoma, myeloid;
Colonic neoplasms
- MeSH:
Colon;
Colonic Neoplasms;
Diagnosis;
Diagnosis, Differential;
Drug Therapy;
Granulocyte Precursor Cells;
Humans;
Intestines*;
Keratins;
Leukemia, Myeloid, Acute;
Peroxidase;
Sarcoma, Myeloid*
- From:The Korean Journal of Gastroenterology
2016;68(3):148-151
- CountryRepublic of Korea
- Language:English
-
Abstract:
Myeloid sarcoma (MS) is an extramedullary involvement of immature myeloid proliferation. An isolated MS is defined as a myeloblastic tumor when it arises without any concomitant circulating disease. A diagnosis of MS is established using pathologic features including infiltration of myeloblasts and strong myeloperoxidase expression with negative cytokeratin immunohistochemical staining. We report a rare case of colonic MS without any peripheral blood abnormality. If the affected patient were left untreated, the MS could evolve into acute myeloid leukemia (AML) within one year. Several studies recommend the same regimens of chemotherapy as used for circulating AML to treat isolated MS. We focused on the diagnosis of MS in this study. The correct diagnosis of MS is important for adequate treatment. In conclusion, MS should be considered in the differential diagnosis of intestinal tumor.
