Research progress on neuroprotective effect and mechanism of spermidine
10.7619/jcmp.20230862
- VernacularTitle:亚精胺的神经保护作用及机制的研究进展
- Author:
Chaoyong WANG
1
;
Deyan CHEN
;
Shuangshi WU
;
Binjia RUAN
;
Wanda ZHAN
;
Fanhao WEI
;
Yongxiang WANG
Author Information
1. 扬州大学医学院,江苏扬州,225001
- Keywords:
spermidine;
polyamine metabolism;
neurological damage disease;
neuroprotec-tion;
research progress
- From:
Journal of Clinical Medicine in Practice
2024;28(2):124-128
- CountryChina
- Language:Chinese
-
Abstract:
Spermidine,as a natural polyamine with high content in nerve cells,plays roles in regulating synaptic plasticity,promoting autophagy,and alleviating oxidative stress in the nervous sys-tem.Spermidine and polyamine metabolism may bring new therapeutic ideas for nervous system injury diseases.This paper reviewed the neuroprotective effects and mechanisms of spermidine in nervous sys-tem injury diseases.
