Research Status on Targeted Therapy for Squamous Cell Lung Cancer
10.3779/j.issn.1009-3419.2013.10.11
- VernacularTitle:肺鳞癌靶向治疗研究现状
- Author:
YUAN HONG
1
;
LU SHUN
Author Information
1. 上海交通大学医学院
- Keywords:
Lung neoplasms;
Squamous cell carcinoma;
Targeted therapy
- From:
Chinese Journal of Lung Cancer
2013;(10):559-563
- CountryChina
- Language:Chinese
-
Abstract:
With the research of driver mutations, targeted therapy for lung cancer has made a great progress. Com-pared with lung adenocarcinoma, treatment of squamous cell lung cancer (SCC) has been far behind. While targeted therapies have improved outcomes for patients with lung adenocarcinoma, such as EGFR-TKIs, EML4-ALK inhibitors, molecularly tar-geted drugs are poorly active for SCC. SCC currently lacks therapeutically exploitable genetic alterations. hTese observations emphasize the need for new driver mutations and“druggable”targets in SCC patients. Combining with the research in recent years, this review will discuss the research status in targeted therapy for SCC.
