Evaluation of Three-Dimensional Reconstruction CT in Percutaneous Radiofrequency Ablation (RFA) of the Unresectable Lung Tumor with a Clustered Electrode
10.3779/j.issn.1009-3419.2009.07.006
- VernacularTitle:CT引导下射频消融治疗中晚期非小细胞肺癌的近期疗效观察
- Author:
LIU BAODONG
1
;
ZHI XIUYI
;
LIU LEI
;
HU MU
;
WANG GUOTIAN
;
XU QINGSHENG
;
ZHANG YI
;
SU LEI
Author Information
1. 首都医科大学宣武医院
- Keywords:
Lung neoplasm;
Catheter ablation;
Tomography;
X-ray coraputed
- From:
Chinese Journal of Lung Cancer
2009;12(7):775-779
- CountryChina
- Language:Chinese
-
Abstract:
Background and objective Radiofrequency ablation (RFA) of lung tumours has recently received much attention for the promising results achieved. Here, to evaluate the value of three-dimensional reconstruction CT in radiofrequen-cy ablation (RFA) of advanced non-small cell lung cancer. Methods Sixty-six cases of advanced non-small ceil lung cancer with 68 lesions (2 patients had 2 lesion treated in one session) were underwent three-dimensional reconstruction CT-giuded percuta-neous RFA therapy. To evaluate short-term therapeutic effect of lung tumors using spiral CT scanning in 1-3 months after RFA to investigate the alterations of minor size and density pre-and post-procedure, and complications, to observe the short-term cura-tive effect. Results Our experiences have shown an initial increase in lesion size at immediate follow-up CT. The density of 64 lesions was lowered (94.1%) and 4 lesion is increased (5.9%) at immediate and one month follow-up CT. SPECT scan findings that 82.4% (56/68) cases of FDG uptake in tumors after RFA with tumor/non-tumor of lower than 2.5 at one month follow-up. The change in treated lesion size over time, radiologically assessed through measurements of the lesions on axial CT scans in the lung window setting no lesions had complete response, 50 lesions (73.5%) had partial response, 2 lesions with stable disease, 6 lesions showed progressive disease at 3 month follow-up CT. SPECT scan findings that 79.4% (54/68) cases of FDG uptake in tumors after RFA with tumor/non-tumor of lower than 2.5 at 3 month follow-up. Conclusion The percutaneons RFA therapy under the guidance of three-dimensionsl reconstruction CT scan is safe and effective, with few complications, and can serve as a new method to the treatment of advanced non-small ceil lung cancers.
