N2 disease in non-small cell lung cancer patients, diagnosis and evaluation: a Turkish chest surgeon's perspective
10.3779/j.issn.1009-3419.2008.05.022
- VernacularTitle:N2 disease in non-small cell lung cancer patients, diagnosis and evaluation: a Turkish chest surgeon's perspective
- Author:
TOKER ALPER
1
Author Information
1. Department of Thoracic Surgery, lstsnbul Medical School, lstanbul University
- Keywords:
Mediastinum Neoplasm staging Lung neoplasms
- From:
Chinese Journal of Lung Cancer
2008;11(5):622-626
- CountryChina
- Language:Chinese
-
Abstract:
Mediastinal or N2 disease is the most important factor in selecting the optimal treatment strategy in patients without distant metastasis. A direct surgical resection has not generally been accepted as a treatment modality in whom media.stinal nodal involvement is demonstrated. Patients with lung cancer can be diagnosed as clinical N2 disease based on CT and PET-CT characteristics of the mediastinum and the clinical presentation. Invasive diagnostic modalities used in the detection of N2 disease are: mediastinoscopy, endoesophageal ultrasound guided biopsy (EUS), transbronchial needle aspiration (TBNA), endobronehial ultrasound guided biopsy (EBUS), video-assisted thoracoscopic surgery (VATS),and mediastinotomy/extended mediastinoacopy. In this article, the author discusses about invasive and noninvasive techniques on the evaluation of mediastinal disease and presents his experience on this topic.