The Application Status and Prospect of Metal Drugs in Antibacterial Field
10.14148/j.issn.1672-0482.2024.0864
- VernacularTitle:金属类化合物在抗菌领域的应用现状及展望
- Author:
Guoheng LI
1
;
Jintao WANG
;
Weiping SHI
;
Xiangwen LIAO
Author Information
1. 江西科技师范大学药学院,江西 南昌 330013
- Keywords:
metal compounds;
metal complexes of Chinese medicine;
antimicrobial activity;
antibacterial mechanism;
research pro-gress
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2024;40(8):864-874
- CountryChina
- Language:Chinese
-
Abstract:
Metal-organic complexes have a long history of clinical application and have shown remarkable efficacy in the treatment of hypertension,skin infections and gastrointestinal diseases.In recent years,the application of metalloids in anti-bacterial infection thera-py and their mechanism of action have been widely studied.In this paper,three commonly used metallodrugs are selected as examples to review the progress and mechanism of metalloids in antibacterial applications,the research of novel metal-based drugs and the metallo-drugs with extracted components of traditional Chinese medicines and their derivatives,and to analyze the potential advantages of metallo-drugs in the field of antibacterial.