Clinical efficiency of laparoscopic ovarian perforation combined with clomiphene citrate and human chorionic gonadotropin in treating infertility induced by polycystic ovary syndrome
10.7619/jcmp.201907027
- VernacularTitle:腹腔镜下卵巢打孔术配合克罗米芬、人绒毛膜促性腺激素对多囊卵巢综合征所致不孕症的临床效果
- Author:
Xiaolin JIA
1
;
Na LI
Author Information
1. 陕西省府谷县中医医院 妇产科
- Keywords:
polycystic ovary syndrome;
infertility;
laparoscope;
ovarian perforation;
clomiphene citrate;
human chorionic gonadotropin
- From:
Journal of Clinical Medicine in Practice
2019;23(7):102-105
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical efficiency of laparoscopic ovarian perforation combined with clomiphene citrate (CC) and human chorionic gonadotropin (HCG) in treating infertility induced by polycystic ovary syndrome (PCOS). Methods Totally 68 patients with infertility induced by PCOS were randomly divided into two groups, with 34 cases in each group. The control group was treated with laparoscopic ovarian perforation and HCG, while the observation group was treated with laparoscopic ovarian perforation combined with CC and HCG. Therapeutic effect and pregnancy condition were compared between the two groups. Results After treatment, the levels of luteinizing hormone, estradiol and testosterone in the observation group were significantly better than those in the control group (P ＜ 0. 05). In the observation group, the ovulation rate and one-year pregnancy rate were 91. 18％ and 58. 82％ respectively, which were significantly higher than 58.82％ and 32. 35％ in the control group (P ＜ 0. 05). There were no adverse reactions in the control group, and the incidence rate of adverse reactions in the observation group was 5. 58％. There was no significant difference between the two groups (P＞ 0. 05). Conclusion Laparoscopic ovarian perforation combined with CC and HCG is effective in the treatment of infertility induced by PCOS, which can improve sex hormone level and increase ovulation rate and pregnancy rate.
