Clinical Study on the Analgesic Effect of Electroacupuncture Combined with Indomethacin Suppository in Transvaginal Ultra-sound-Guided Oocyte Retrieval
10.14148/j.issn.1672-0482.2024.0628
- VernacularTitle:电针联合吲哚美辛栓在经阴道超声引导下穿刺取卵术中镇痛作用的临床研究
- Author:
Yixin WANG
1
;
Yanyun YIN
;
Yujia KOU
;
Yumeng DONG
;
Yanni ZHANG
;
Zhihao GAO
;
Xiaocui LIU
Author Information
1. 南京中医药大学第一临床医学院,江苏 南京 210023
- Keywords:
in vitro fertilization-embryo transfer;
transvaginal ultrasound-guided oocyte retrieval;
electroacupuncture;
tenderness threshold;
acupuncture analgesia;
Hegu;
Neiguan
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2024;40(6):628-632
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To observe the auxiliary analgesic effect of electroacupuncture at Hegu and Neiguan combined with in-domethacin suppository in patients undergoing transvaginal ultrasound-guided oocyte retrieval(TUGOR and its effect on the outcome of in vitro fertilization(IVF.METHODS 64 IVF-ET patients undergoing TUGOR were randomly divided into a treatment group and a control group,32 cases in each group.One case dropped out of the treatment group during the treatment.The control group was given indomethacin suppository rectal administration,and the treatment group was given electroacupuncture at Hegu and Neiguan in addition to the treatment of the control group.The patients'tenderness threshold,VAS score,pain grade score,respiratory rate,and pulse rate were evaluated before and after TUGOR operation.The number of oocytes obtained,the rate of two pronuclei(2PN,embryo utiliza-tion rate,and high-quality embryo rate were evaluated after TUGOR operation.The adverse reactions of the two groups were monitored during and after operation.RESULTS After TUGOR operation,the VAS score and pain grade of the treatment group were signifi-cantly lower than those of the control group(P<0.01;the tenderness threshold of the two groups was significantly reduced after opera-tion(P<0.05,P<0.01,and the treatment group was better than the control group(P<0.05;the incidence of nausea during opera-tion,abdominal distension and nausea 48 h after operation in the treatment group were better than those in the control group(P<0.05;the high-quality embryo rate in the treatment group was better than that in the control group(P<0.05.CONCLUSION Electroacupuncture at Hegu and Neiguan combined with indomethacin suppository can effectively assist in analgesia,and can reduce the incidence of adverse reactions during and after TUGOR to varying degrees,and may have certain advantages in improving the rate of high-quality embryos.