The long-term outcome and prognostic factors analysis of multimodality treatment for 283 patients with thymoma

VernacularTitle:283例胸腺瘤的综合治疗结果及预后因素分析
Author: Kai-Liang WU ¹ ; Guo-Liang JIANG ; Jing-Fang MAO ; Xiao-Long FU ; Hao QIAN
Author Information

1. 复旦大学附属肿瘤医院
Keywords: Thymoma; Surgery; Radiotherapy; Prognosis
From: Chinese Journal of Oncology 2008;30(1):69-71
CountryChina
Language:Chinese
Abstract: Objective To study the long-term outcome and prognostic factors in patients with thymoma treated with multimodality therapy. Methods 283 patients with pathologically confirmed thymoma were enrolled into this study. Overall survival rate and local control rate were calculated. Cox regression model was used to analyze the prognostic factors. Results The 5-year overall survival rate was 94.3%, 86.3%, 71.6%, 39.4% and 80.4% for patients with stage Ⅰ,Ⅱ,Ⅲ, Ⅳ disease and all patients, respectively. The 10-year overall survival rate was 84.3%, 75.4%, 56.6% , 29.6% and 68.4% for stage Ⅰ,Ⅱ,Ⅲ, Ⅳ disease and all patients. The Masaoka staging, resection extent, and gender were independent prognositic factors in multivariate analysis. Conclusion The Masaoka staging and resection extent are independent prognositic factors in patients with thymoma treated with multimodality therapy.