Functional Substance of Chinese Medicine and Targeted Therapy Strategies
10.14148/j.issn.1672-0482.2018.0025
- VernacularTitle:中药功效物质与靶向治疗策略
- Author:
Hong-Zhi QIAO
1
;
Lei ZHANG
;
Juan SUN
;
Liu-Qing DI
Author Information
1. 南京中医药大学药学院
- Keywords:
functional substance of Chinese medicine;
effective components;
the theory of guiding medicinals;
compatibility law;
in vivo distribution;
targeted drug delivery;
mechanism of action
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2018;34(1):25-29
- CountryChina
- Language:Chinese
-
Abstract:
Chinese medicine and targeted therapy belong to two different disciplinary systems.They have both differences and multiple connections and potential for integration.This is mainly reflected in the interconnectedness of the theoretical system,the syntropy of the purpose and the complementarity of the practical means.Targeted treatment of functional substance of Chinese medicine can be understood from two perspectives.On the one hand,many active ingredients derived from Chinese medicine have difficulties in druggability,which can be solved using the modern targeted technology for enhancing the efficacy and reducing the side effects.On the other hand,under the guiding thought of Chinese medicine,many functional substances of Chinese medicine endow drugs or preparations orientation to the specific regions,leading to the improved therapeutic effect.In this review,we summarize the research progress in recent years from the above two aspects in order to understand and discover the intrinsic relationship between them and the potential value of development,which will promote the integration development of Chinese medicine and pharmaceutics.
