Related factors and treatment of gastroparesis syndrome after radical distal gastrectomy in patients with gastric cancer
10.7619/jcmp.201807014
- VernacularTitle:胃癌患者根治性远端胃大部切除术后胃瘫综合征的相关因素及治疗方案
- Author:
Qiang ZHANG
1
;
Dongsheng HOU
;
Libin YAO
;
Chao LI
;
Hui WANG
;
Song MENG
;
Jian HONG
;
Yong SHAO
;
Xiaocheng ZHU
Author Information
1. 徐州医科大学附属医院胃肠外科
- Keywords:
distal gastrectomy;
gastroparesis syndrome;
factors;
treatment
- From:
Journal of Clinical Medicine in Practice
2018;22(7):53-56
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the related factors of gastroparesis syndrome after radical distal gastrectomy and the curative effect of different treatment regimens.Methods Univariate analysis and unconditional multivariate Logistic regression analysis werc used to analyze the influencing factors in 41 patients with postsurgical gastroparesis syndrome (PGS) and 719 patients without PGS.Results There were significant differences in surgical methods,gastrointestinal reconstruction,pyloric obstruction,abdominal infection,postoperative hyperglycemia,postoperative low protein,postoperative anemia,postoperative nutrition,operation time and bleeding volume between PGS patients and non-PGS patients (P ＜ 0.05).Multivariate Logistic regression analysis showed that patients with Billroth-Ⅱ gastrointestinal reconstruction,abdominal infection,postoperative hyperglycemia,postoperative anemia,postoperative low protein,prolonged operation,and bleeding were risk factors for PGS (OR ＞ 1,P ＜ 0.05).Laparoscopic surgery was the protective factor of gastroparesis (OR ＜ 1,P ＜ 0.05).The recovery time of combined drug therapy was significantly better than that of single drug (P ＜ 0.05).The length of hospital stay and hospitalization expense in PGS group were significantly higher than non-PGS group.Conclusion Avoidance of the above risk factors in perioperative period can prevent the occurrence of gastroparesis.Combined treatment can accelerate the recovery of gastroparesis.
