Effect of trinity pharmaceutical care for first-episode schizophrenic patients
10.7619/jcmp.201806006
- VernacularTitle:首发精神分裂症患者应用三位一体药学服务的效果研究
- Author:
Xiangming CAI
1
;
Xiaoyu SHAN
;
Lili WANG
;
Xiaoyu SUN
Author Information
1. 江苏省南通市第四人民医院药剂科
- Keywords:
trinity pharmaceutical care;
schizophrenia;
medication compliance;
quality of life
- From:
Journal of Clinical Medicine in Practice
2018;22(6):19-22
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the influence of the trinity pharmaceutical care intervention on medicine compliance,quality of life,the recurrence rate and re-hospitalization rate of first-episode schizophrenic patients.Methods A total of 60 first-episode schizophrenics in our hospital were randomly divided into control group and intervention group,with 30 patients in each group,all of these patients received routine antipsychotic treatment,and the intervention group was additionally given antipsychotic medication.The treatment compliance,the World Health Organization quality of life-BREF (WHOQOL-BREF) scores,the recurrence rate and re-hospitalization rate were assessed on admission,at discharge and at 3 months and 6 months after discharge.Results There were no significant differences in drug compliance and scores of WHOQOL between the two groups on admission (P ＞ 0.05).The medication compliance of intervention group was remarkably higher than that in the control group (P ＜ 0.05),the recurrence rate and re-hospitalization rate had no significant differences (P ＞ 0.05),the scores of physiology,psychology,social relations and environment of WHOQOL in the intervention group were obviously higher than that in the control group after 3 months of discharge (P ＜ 0.05).At 6 months after discharge,the medication compliance of intervention group was evidently higher than that in the control group (P ＜ 0.01),the recurrence rate was lower than the control group (P ＜ 0.05),and there was no significant difference in re-hospitalization rate between two groups (P ＞ 0.05),while the scores of physiology,psychology,social relations and environment of WHOQOL in intervention group weresignificantly higher than that in the control group (P ＜ 0.01).Conclusion Trinity pharmaceutical care can improve the medication compliance and reduce the recurrence rate of patients with first-episode schizophrenia,and improve patients' quality of life,so it can be used as an effective method for rehabilitation of schizophrenia patients.
