Clinical Research on Methods of Tonifying qi, Dispelling Dampness and Removing Toxin in Treating Cervical HPV Infection
10.14148/j.issn.1672-0482.2017.0232
- VernacularTitle:益气除湿解毒汤治疗宫颈HPV感染的临床研究
- Author:
Hong SUN
1
;
Qin-Xian ZHU
;
Bo-Lin GU
Author Information
1. 苏州大学附属第二医院
- Keywords:
methods of tonifying qi;
dispelling dampness and removing toxin;
treatment;
HPV;
cervical intraepithelial neoplasm
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2017;33(3):232-234
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To explore the clinical efficiency of methods of tonifying qi, dispelling dampness and removing toxin in treating cervical human papillomavirus(HPV) infection.METHODS 170 cases with HR-HPV positive infection catering for TCM leukorrheal disease of qi deficiency and damp-heat or damp-toxin accumulation type were selected from patients who visited the gynecological clinic in our hospital between February, 2010 and January, 2014 and divided into three groups according to results of "three step" diagnosis, that was, cytological screening-vaginoscopy-histopathological examination.To be specific, Group A was HR-HPV with negative result of thinprep cytologic test(TCT), with group B being HR-HPV withⅠdegree of cervical intraepithelial neoplasm(CIN) , and group C being HR-HPV withⅡto Ⅲ degree of cervical intraepithelial neoplasm(CIN).Then the three groups were further divided into the treatment group of A1, BI, C1 and the control group of A2, B2, C2.Group A1 and B1 in the treatment group were given the oral decoction of tonifying qi, dispelling dampness and removing toxin, combined with compound sea buckthorn seed oil suppository for vaginal use.While group C1 was given oral decoction of tonifying qi, dispelling dampness and removing toxin, combined with compound sea buckthorn seed oil suppository for vaginal use after the loop electrosurgical excision procedure(LEEP).Patients of the group A2, B2 in the control group received follow up observation without any treatment voluntarily, and group C2 received the follow-up observation after LEEP.RESULTS The syndrome integrals of group A1 and B1 after three courses' treatment were significantly different from those before treatment(P<0.05).The HPV seroconversion rates of the three groups in the treatment group were evidently distinguished from those of the control group(P<0.05).CONCLUSION Methods for tonifying qi, dispelling dampness and removing toxin is efficient in curing HPV infection, with enjoyable therapeutic results.
