Clinical value of Reinforcing Qi and Blood Decoction combined with entecavir in treatment of hepatitis B cirrhosis and hypersplenism
10.7619/jcmp.201805004
- VernacularTitle:益气和血方联合恩替卡韦治疗乙肝肝硬化脾功能亢进的临床价值研究
- Author:
Changjiang YE
1
Author Information
1. 湖北省仙桃市第一人民医院中医科
- Keywords:
Qi and Blood Decoction;
entecavir;
hepatitis B cirrhosis;
hypersplenism;
TCM syndrome score
- From:
Journal of Clinical Medicine in Practice
2018;22(5):13-15,22
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effect of Reinforcing Qi and Blood Decoction combined with entecavir in treatment of hepatitis B cirrhosis and hypersplenism.Methods A total of 116 liver cirrhosis and hypersplenism patients were divided into two groups,the control group (n =58) was given entecavir treatment,and the observation group (n =58) applied Reinforcing Qi and Blood Decoction treatment,the changes of relevant indicators were observed after the treatment.Results Hypochondriac pain,abdominal distension,nausea,anorexia,lassitude,depression,loose stools were significantly improved (P ＜ 0.05),and the above indexes of the observation group was significantly lower than that in the control group (P ＜ 0.05).After treatment,white blood count (WBC)and platelets (PLT) were significantly increased,spleen length,thickness of spleen,main portal vein (MPV) and splenic vein diameter (SPV) were significantly lower than treatment before (P ＜0.05),and above indicators of the observation group was significantly better than that in the control group (P ＜ 0.05).The curative effect,and total efficiency of the observation group were significantly higher than that in the control group (P ＜ 0.05).Conclusion Reinforcing Qi and Blood Decoction combined with entecavir has obvious clinical outcomes in the treatment of hepatitis B cirrhosis and hypersplenism.
