Effect analysis of pernasal heated humidified high flow oxygen therapy in treating children with severe pneumonia
10.7619/jcmp.201803039
- VernacularTitle:经鼻加温湿化氧疗在儿童重症肺炎中的疗效分析
- Author:
Xuemei XU
1
;
Yingjia JIANG
;
Hong SHI
;
Xiaochun HE
Author Information
1. 四川省妇幼保健院重症医学科
- Keywords:
pernasal heated humidified high flow oxygen therapy;
severe pneumonia;
children
- From:
Journal of Clinical Medicine in Practice
2018;22(3):131-133
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinical effect of pernasal heated humidified high flow oxygen therapy (HFNC) on treating children with severe pneumonia.Methods For the children with severe pneumonia by treatment of HFNC in PICU in 2016,the changes of respiratory rate,heart rate,p(O2) and p(CO2) after one hour of HFNC and intubation rate,time of oxygen therapy and curative rate were analyzed.Results The HFNC was able to alleviate the respiratory rate,heart rate and increased p (O2) significantly (P < 0.05),and for children with severe pneumonia complicated with type Ⅱ respiratory failure,the HFNC also can reduced p (CO2) significantly (P < 0.05).There was no significant difference of intubation rate between children with type Ⅰ and Ⅱ respiratory failure,but both were significantly higher than children without respiratory failure (P < 0.05).The mean oxygen therapy time of children with type Ⅱ respiratory failure was 7.38 d,which was significantly longer than 5.45 d of children with type Ⅰ respiratory failure and 4.45 d of children without respiratory failure (P < 0.05).The curative rate was 100%.Conclusion HFNC can effectively relieve the respiratory rate,heart rate and hypoxemia in children with severe pneumonia.It can also significantly reduce p(CO2) in children with type Ⅱ respiratory failure.