Effects of Taohong Siwu Decoction on Inflammatory Factors and Hemorheology in Patients with Femoral Shaft Fracture After Sur-gery
10.14148/j.issn.1672-0482.2016.0419
- VernacularTitle:桃红四物汤对股骨干骨折术后炎性因子和血液流变学的影响
- Author:
Jin-Hua MAO
1
;
Gang-Cheng TU
;
Jing QIU
;
Ping SUN
Author Information
1. 松滋市人民医院骨科
- Keywords:
Taohong Siwu Decoction;
femoral shaft fracture;
inflammatory factors;
hemorheology;
qi stagnation and blood stasis
- From:
Journal of Nanjing University of Traditional Chinese Medicine
2016;32(5):419-421,497
- CountryChina
- Language:Chinese
-
Abstract:
ABSTRACT:OBJECTIVE To explore the effects of Taohong Siwu Decoction on inflammatory factors and hemorheology in patients with femoral shaft fracture after surgery.METHODS 79 patients with femoral shaft fracture after surgery in the con-trol group were treated with conventional therapy while the equal number of patients in the study group were given Taohong Si-wu Decoction.The clinical curative effect,TCM syndrome,interleukin-1(IL-1),interleukin-6(IL-6),tumor necrosis factor-α(TNF-α),whole blood high shear viscosity(ηhigh),whole blood midst shear viscosity(ηmidst),whole blood low shear viscos-ity(ηlow),plasma viscosity(ηplasm),hematocrit value(HCT),white blood cell(WBC) count and sedimentation equation-K value of both groups were compared.RESULTS The total curative effects of study group and control group were 97.02% and 79.75% respectively(P <0.01).Both groups experienced a decrease in pain,swelling,ecchymosis,IL1,IL6,TNFα,ηhigh,ηmidst,ηlow,ηplasm,HCT,WBC and sedimentation equation-K value and the treatment group was more superior to the control group(P <0.05~0.01).CONCULSION Taohong Siwu Decoction can significantly inhibit the inflammatory response and improve hemorheology indexes and clinical symptom for patients with femoral shaft fracture after surgery.